HSD17B10 抗体 (AA 14-48)
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北京 101111
Quick Overview for HSD17B10 抗体 (AA 14-48) (ABIN7870643)
抗原
See all HSD17B10 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 14-48
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原理
- ERAB Antibody / HSD17B10 (N-Terminal Region)
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纯化方法
- Antigen affinity
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免疫原
- A portion of amino acids 14-48 from human ERAB was used as the immunogen for the ERAB antibody.
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亚型
- Ig Fraction
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anti-Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10) antibody
HSD17B10 适用: 人, 猴 WB, IHC, IF, FACS, IHC (p) 宿主: 小鼠 Monoclonal 5E2 unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10) (C-Term) antibodyHSD17B10 适用: 人 WB, IF, ICC, IHC (p), IHC (wm) 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10) (AA 48-261) antibodyHSD17B10 适用: 人 WB, IHC, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10) (AA 48-261) antibodyHSD17B10 适用: 人 WB, FACS, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10) (AA 140-172) antibodyHSD17B10 适用: 人, 小鼠, 大鼠 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB56913 unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10) (AA 1-261) antibodyHSD17B10 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10) antibodyKD Validated HSD17B10 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 25GB5705 unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10) antibodyHSD17B10 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10) (AA 14-48) antibodyHSD17B10 适用: 人 WB, IF, FACS 宿主: 兔 Polyclonal RB56756 unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10) (AA 1-261) antibodyHSD17B10 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- The stated application concentrations are suggested starting points. Titration of the ERAB antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the ERAB antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- HSD17B10 (Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10))
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别名
- ERAB
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背景
- ERAB / HSD17B10 functions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1/TRMT10C, MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their 5'-ends. Catalyzes the beta-oxidation at position 17 of androgens and estrogens and has 3-alpha-hydroxysteroid dehydrogenase activity with androsterone. Catalyzes the third step in the beta-oxidation of fatty acids. Carries out oxidative conversions of 7-alpha-OH and 7-beta-OH bile acids. Also exhibits 20-beta-OH and 21-OH dehydrogenase activities with C21 steroids. By interacting with intracellular amyloid-beta, it may contribute to the neuronal dysfunction associated with Alzheimer disease (AD). [UniProt]
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UniProt
- Q99714
抗原
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