RCC1 抗体 (AA 14-421)
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Quick Overview for RCC1 抗体 (AA 14-421) (ABIN7870639)
抗原
See all RCC1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 14-421
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原理
- RCC1 Antibody / Regulator of Chromosome Condensation
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纯化方法
- Affinity purified
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免疫原
- Recombinant human protein (amino acids A14-S421) was used as the immunogen for the RCC1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the RCC1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the RCC1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- RCC1 (Regulator of Chromosome Condensation 1 (RCC1))
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别名
- RCC1
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背景
- CHC1, also named as RCC1, SNHG3-RCC1, promotes the exchange of ran-bound gdp by gtp. It is involved in the regulation of onset of chromosome condensation in the S-phase. Phosphorylation of RCC1 on serines located in or near its nuclear localization signal activates RCC1 to generate RanGTP on mitotic chromosomes, which is required for spindle assembly and chromosome segregation. This antibody is a rabbit polyclonal antibody raised against residues near the C terminus of human RCC1. The geneID has updated as 1104 recently.
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UniProt
- P18754
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途径
- Chromatin Binding, Protein targeting to Nucleus
抗原
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