PRDM8 抗体 (AA 14-405)
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Quick Overview for PRDM8 抗体 (AA 14-405) (ABIN7870635)
抗原
See all PRDM8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 14-405
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原理
- PRDM8 Antibody / PR domain zinc finger protein 8
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纯化方法
- Antigen affinity purified
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免疫原
- E. coli-derived recombinant human protein (amino acids D14-D405) was used as the immunogen for the PRDM8 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the PRDM8 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the PRDM8 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- PRDM8 (PR Domain Containing 8 (PRDM8))
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别名
- PRDM8
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背景
- This gene encodes a protein that belongs to a conserved family of histone methyltransferases that predominantly act as negative regulators of transcription. The encoded protein contains an N-terminal Su(var)3-9, Enhancer-of-zeste, and Trithorax (SET) domain and a double zinc-finger domain. Knockout of this gene in mouse results in mistargeting by neurons of the dorsal telencephalon, abnormal itch-like behavior, and impaired differentiation of rod bipolar cells. In humans, the protein has been shown to interact with the phosphatase laforin and the ubiquitin ligase malin, which regulate glycogen construction in the cytoplasm. Alternative splicing results in multiple transcript variants.
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UniProt
- Q9NQV8
抗原
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