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PRDM8 抗体 (AA 14-405)

The 兔 多克隆 anti-PRDM8 antibody is suitable to detect PRDM8 in samples from 人. It has been validated for WB, ELISA, IF 和 FACS.
产品编号 ABIN7870635
发货至: 中国
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Quick Overview for PRDM8 抗体 (AA 14-405) (ABIN7870635)

抗原

See all PRDM8 抗体
PRDM8 (PR Domain Containing 8 (PRDM8))

适用

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宿主

  • 20

克隆类型

  • 20
多克隆

标记

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This PRDM8 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)
  • 抗原表位

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    AA 14-405

    原理

    PRDM8 Antibody / PR domain zinc finger protein 8

    纯化方法

    Antigen affinity purified

    免疫原

    E. coli-derived recombinant human protein (amino acids D14-D405) was used as the immunogen for the PRDM8 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the PRDM8 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the PRDM8 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    PRDM8 (PR Domain Containing 8 (PRDM8))

    别名

    PRDM8

    背景

    This gene encodes a protein that belongs to a conserved family of histone methyltransferases that predominantly act as negative regulators of transcription. The encoded protein contains an N-terminal Su(var)3-9, Enhancer-of-zeste, and Trithorax (SET) domain and a double zinc-finger domain. Knockout of this gene in mouse results in mistargeting by neurons of the dorsal telencephalon, abnormal itch-like behavior, and impaired differentiation of rod bipolar cells. In humans, the protein has been shown to interact with the phosphatase laforin and the ubiquitin ligase malin, which regulate glycogen construction in the cytoplasm. Alternative splicing results in multiple transcript variants.

    UniProt

    Q9NQV8
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