PCDHGA2 抗体 (AA 132-444)
Our Local Distributor
北京 101111
Quick Overview for PCDHGA2 抗体 (AA 132-444) (ABIN7870515)
抗原
See all PCDHGA2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 132-444
-
原理
- PCDHGA2 Antibody / Protocadherin gamma A2
-
纯化方法
- Antigen affinity chromatography
-
免疫原
- An E.coli-derived human recombinant protein (amino acids R132-D444) was used as the immunogen for the PCDHGA2 antibody.
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal dilution of the PCDHGA2 antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
-
储存条件
- 4 °C,-20 °C
-
储存方法
- After reconstitution, the PCDHGA2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
-
-
- PCDHGA2 (Protocadherin gamma Subfamily A, 2 (PCDHGA2))
-
别名
- PCDHGA2
-
背景
- This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
-
UniProt
- Q9Y5H1
抗原
-