Choline Acetyltransferase 抗体 (AA 131-704)
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Quick Overview for Choline Acetyltransferase 抗体 (AA 131-704) (ABIN7870510)
抗原
See all Choline Acetyltransferase (CHAT) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 131-704
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原理
- Choline Acetyltransferase Antibody / ChAT
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids L131-S704) was used as the immunogen for the Choline Acetyltransferase antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the Choline Acetyltransferase antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Choline Acetyltransferase antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- Choline Acetyltransferase (CHAT) (Choline O-Acetyltransferase (CHAT))
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别名
- Choline Acetyltransferase
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背景
- Choline acetyltransferase (commonly abbreviated as ChAT, but sometimes CAT) is a transferase enzyme responsible for the synthesis of the neurotransmitter acetylcholine. In humans, the choline acetyltransferase enzyme is encoded by the CHAT gene. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform.
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UniProt
- P28329
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途径
- Skeletal Muscle Fiber Development
抗原
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