Erythrocyte Ankyrin 抗体 (AA 1300-1844)
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Quick Overview for Erythrocyte Ankyrin 抗体 (AA 1300-1844) (ABIN7870500)
抗原
See all Erythrocyte Ankyrin (ANK1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1300-1844
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原理
- Ankyrin-1 Antibody / ANK1 / Erythrocyte
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids N1300-Q1844) was used as the immunogen for the Ankyrin-1 antibody.
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亚型
- IgG1
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anti-Ankyrin 1, Erythrocytic (ANK1) (AA 1-1881) antibody (Atto 390)
ANK1 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S388A-10 Atto 390
anti-Ankyrin 1, Erythrocytic (ANK1) (AA 1-1881) antibody (Atto 488)ANK1 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S388A-10 Atto 488
anti-Ankyrin 1, Erythrocytic (ANK1) (AA 1-1881) antibody (Atto 594)ANK1 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S388A-10 Atto 594
anti-Ankyrin 1, Erythrocytic (ANK1) (AA 1-1881) antibody (Biotin)ANK1 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S388A-10 Biotin
anti-Ankyrin 1, Erythrocytic (ANK1) (AA 1-1881) antibody (APC)ANK1 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S388A-10 APC
anti-Ankyrin 1, Erythrocytic (ANK1) (AA 1-1881) antibody (HRP)ANK1 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S388A-10 HRP
anti-Ankyrin 1, Erythrocytic (ANK1) (AA 1-1881) antibody (PerCP)ANK1 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S388A-10 PerCP
anti-Ankyrin 1, Erythrocytic (ANK1) (AA 1-1881) antibody (FITC)ANK1 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S388A-10 FITC
anti-Ankyrin 1, Erythrocytic (ANK1) (AA 1-1881) antibody (PE)ANK1 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S388A-10 PE
anti-Ankyrin 1, Erythrocytic (ANK1) (AA 1-1881) antibodyANK1 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S388A-10 unconjugated
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应用备注
- Optimal dilution of the Ankyrin-1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Ankyrin-1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- Erythrocyte Ankyrin (ANK1) (Ankyrin 1, Erythrocytic (ANK1))
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别名
- Ankyrin-1
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背景
- Ankyrin 1, erythrocytic, also known as ANK1, is a protein that in humans is encoded by the ANK1 gene. Ankyrins are a family of proteins that link the integral membrane proteins to the underlying spectrin-actin cytoskeleton and play key roles in activities such as cell motility, activation, proliferation, contact and the maintenance of specialized membrane domains. Multiple isoforms of ankyrin with different affinities for various target proteins are expressed in a tissue-specific, developmentally regulated manner. Most ankyrins are typically composed of three structural domains: an amino-terminal domain containing multiple ankyrin repeats, a central region with a highly conserved spectrin binding domain, and a carboxy-terminal regulatory domain which is the least conserved and subject to variation. Ankyrin 1, the prototype of this family, was first discovered in the erythrocytes, but since has also been found in brain and muscles. Mutations in erythrocytic ankyrin 1 have been associated in approximately half of all patients with hereditary spherocytosis. Complex patterns of alternative splicing in the regulatory domain, giving rise to different isoforms of ankyrin 1 have been described. Truncated muscle-specific isoforms of ankyrin 1 resulting from usage of an alternate promoter have also been identified.
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UniProt
- P16157
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途径
- Synaptic Membrane
抗原
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