Claudin 6 抗体 (AA 130-159)
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Quick Overview for Claudin 6 抗体 (AA 130-159) (ABIN7870491)
抗原
See all Claudin 6 (CLDN6) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 130-159
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原理
- Claudin 6 Antibody / CLDN6
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 130-159 from the human protein was used as the immunogen for the Claudin 6 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the Claudin 6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Claudin 6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Claudin 6 (CLDN6)
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别名
- Claudin 6
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背景
- Claudin 6 is a protein that in humans is encoded by the CLDN6 gene. It belongs to the group of claudins. Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16.
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UniProt
- Q99808
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途径
- Hepatitis C
抗原
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