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IL-31 抗体 (AA 13-40)

The 兔 多克隆 anti-IL-31 antibody is suitable to detect IL-31 in samples from 人. It has been validated for WB, IHC (p) 和 FACS.
产品编号 ABIN7870473
发货至: 中国
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北京 101111
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Room 801-803
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Quick Overview for IL-31 抗体 (AA 13-40) (ABIN7870473)

抗原

See all IL-31 (IL31) 抗体
IL-31 (IL31) (Interleukin 31 (IL31))

适用

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宿主

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克隆类型

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多克隆

标记

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This IL-31 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
  • 抗原表位

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    AA 13-40

    原理

    IL-31 Antibody / Interleukin 31

    纯化方法

    Antigen affinity

    免疫原

    A portion of amino acids 13-40 from the human protein was used as the immunogen for the IL-31 antibody.

    亚型

    Ig Fraction
  • 应用备注

    The stated application concentrations are suggested starting points. Titration of the IL-31 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the IL-31 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    IL-31 (IL31) (Interleukin 31 (IL31))

    别名

    IL-31

    背景

    Interleukin 31 (IL-31) is a cytokine that plays a critical role in inflammatory responses and allergic reactions in the body. IL-31 is produced by T-helper 2 (Th2) cells, which are involved in the body's response to allergens and parasites. When released, IL-31 binds to receptors on various cells in the body, triggering a cascade of inflammatory responses that can lead to symptoms such as itching, redness, and swelling. Studies have shown that IL-31 is particularly important in the development of atopic dermatitis, a common skin condition characterized by itchy, inflamed skin. In individuals with atopic dermatitis, levels of IL-31 are often elevated in the skin, leading to increased inflammation and itching. Additionally, IL-31 has also been implicated in other inflammatory conditions such as asthma and inflammatory bowel disease, highlighting its importance in the body's immune response.

    UniProt

    Q6EBC2
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