IL-31 抗体 (AA 13-40)
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北京 101111
Quick Overview for IL-31 抗体 (AA 13-40) (ABIN7870473)
抗原
See all IL-31 (IL31) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 13-40
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原理
- IL-31 Antibody / Interleukin 31
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纯化方法
- Antigen affinity
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免疫原
- A portion of amino acids 13-40 from the human protein was used as the immunogen for the IL-31 antibody.
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亚型
- Ig Fraction
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应用备注
- The stated application concentrations are suggested starting points. Titration of the IL-31 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the IL-31 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- IL-31 (IL31) (Interleukin 31 (IL31))
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别名
- IL-31
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背景
- Interleukin 31 (IL-31) is a cytokine that plays a critical role in inflammatory responses and allergic reactions in the body. IL-31 is produced by T-helper 2 (Th2) cells, which are involved in the body's response to allergens and parasites. When released, IL-31 binds to receptors on various cells in the body, triggering a cascade of inflammatory responses that can lead to symptoms such as itching, redness, and swelling. Studies have shown that IL-31 is particularly important in the development of atopic dermatitis, a common skin condition characterized by itchy, inflamed skin. In individuals with atopic dermatitis, levels of IL-31 are often elevated in the skin, leading to increased inflammation and itching. Additionally, IL-31 has also been implicated in other inflammatory conditions such as asthma and inflammatory bowel disease, highlighting its importance in the body's immune response.
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UniProt
- Q6EBC2
抗原
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