Glutathione Peroxidase 1 抗体 (AA 13-203)
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Quick Overview for Glutathione Peroxidase 1 抗体 (AA 13-203) (ABIN7870458)
抗原
See all Glutathione Peroxidase 1 (GPX1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 13-203
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原理
- Glutathione Peroxidase 1 Antibody / GPX1
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纯化方法
- Antigen affinity purified
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免疫原
- E. coli-derived recombinant human protein (amino acids A13-A203) was used as the immunogen for the Glutathione Peroxidase 1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the Glutathione Peroxidase 1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Glutathione Peroxidase 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- Glutathione Peroxidase 1 (GPX1)
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别名
- Glutathione Peroxidase 1
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背景
- Glutathione peroxidase 1, also known as, GPX-1 is an enzyme that in humans is encoded by the GPX1 gene. It is mapped to 3p21.31. This gene encodes a member of the glutathione peroxidase family, consisting of eight known glutathione peroxidases (Gpx1-8) in humans. Glutathione peroxidase functions in the detoxification of hydrogen peroxide, and is one of the most important antioxidant enzymes in humans. It has been reported that the protein encoded by this gene protects from CD95-induced apoptosis in cultured breast cancer cells and inhibits 5-lipoxygenase in blood cells, and its overexpression delays endothelial cell growth and increases resistance to toxic challenges. GPX1 is one of only a few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by the nonsense (stop) codon TGA.
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UniProt
- P07203
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途径
- Thyroid Hormone Synthesis, Sensory Perception of Sound, Skeletal Muscle Fiber Development, Cell RedoxHomeostasis, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interactome
抗原
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