TTC39B 抗体 (AA 129-682)
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Quick Overview for TTC39B 抗体 (AA 129-682) (ABIN7870445)
抗原
See all TTC39B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 129-682
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原理
- TTC39B Antibody / C9orf52
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纯化方法
- Antigen affinity purified
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免疫原
- E. coli-derived recombinant human protein (amino acids K129-D682) was used as the immunogen for the TTC39B antibody.
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亚型
- IgG
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anti-Tetratricopeptide Repeat Domain 39B (TTC39B) (AA 625-654), (C-Term) antibody
TTC39B 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB27799 unconjugated
anti-Tetratricopeptide Repeat Domain 39B (TTC39B) (AA 1-616) antibodyTTC39B 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Tetratricopeptide Repeat Domain 39B (TTC39B) (AA 10-122) antibodyTTC39B 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Tetratricopeptide Repeat Domain 39B (TTC39B) (AA 378-427) antibodyTTC39B 适用: 人, Cow, 犬, 豚鼠, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Tetratricopeptide Repeat Domain 39B (TTC39B) (AA 559-588), (C-Term) antibodyTTC39B 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the TTC39B antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the TTC39B antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- TTC39B (Tetratricopeptide Repeat Domain 39B (TTC39B))
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别名
- TTC39B
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背景
- Tetratricopeptide repeat protein 39B is a protein that in humans is encoded by the TTC39B gene. TTC39B protein contains two TPR repeats (aa 39 3-426 and 626 -659). TCC39B protein is the product of a high density lipoprotein (HDL) gene that promotes the ubiquitination and degradation of liver X receptor (LXR). TTC39B null or deficient mice challenged with high fat/cholesterol/bile salt diet exhibit increased LX R protein and target gene expression. TTC39B deficiency is reported to stabilize LXR by reducing its polyubiquitination and proteasomal degradation. Hence it reduces the incidence of atherosclerosis and steatohepatitis. TTC39B deficiency mice display higher levels of HDL and Apoplipoprotein A-1 and lower levels of hepatic triglyceride synthesis.However it does not affect glucose tolerance or hepatic gluconeogenesis.
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UniProt
- Q5VTQ0
抗原
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