AMOTL2 抗体 (AA 126-152)
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Quick Overview for AMOTL2 抗体 (AA 126-152) (ABIN7870388)
抗原
See all AMOTL2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 126-152
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原理
- AMOTL2 Antibody / Angiomotin-like protein 2
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纯化方法
- Antigen affinity
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免疫原
- A portion of amino acids 126-152 from the human protein was used as the immunogen for the AMOTL2 antibody.
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亚型
- Ig Fraction
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应用备注
- The stated application concentrations are suggested starting points. Titration of the AMOTL2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the AMOTL2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- AMOTL2 (Angiomotin Like 2 (AMOTL2))
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别名
- AMOTL2
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背景
- AMOTL2 is a member of the angiomotin family of proteins, which are involved in the development and maintenance of blood vessels. It functions as a scaffold protein that helps to organize signaling pathways involved in cell growth and movement. Studies have shown that AMOTL2 is essential for normal development and function of multiple tissues and organs, including the heart, lungs, and kidneys. One of the most intriguing aspects of AMOTL2 is its potential role in cancer progression. Research has shown that dysregulation of AMOTL2 expression is associated with various types of cancer, including breast, lung, and prostate cancer. In some cases, AMOTL2 acts as a tumor suppressor, inhibiting cancer cell growth and metastasis. In other cases, it can promote tumor progression by enhancing angiogenesis and invasiveness.
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UniProt
- Q9Y2J4
抗原
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