MMP1 抗体 (AA 124-469)
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Quick Overview for MMP1 抗体 (AA 124-469) (ABIN7870367)
抗原
See all MMP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 124-469
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原理
- MMP1 Antibody
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纯化方法
- Affinity purified
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免疫原
- A human recombinant protein (amino acids D124-N469) was used as the immunogen for the MMP1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the MMP1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the MMP1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- MMP1 (Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1))
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别名
- MMP1
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背景
- Matrix metalloproteinase-1 (MMP-1), also known as interstitial collagenase and fibroblast collagenase,is an enzyme that in humans is encoded by the MMP1 gene. MMP-1 was the first vertebrate collagenase both purified to homogeneity as a protein, and cloned as a cDNA. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. It is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants.
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UniProt
- P03956
抗原
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