SKAP2 抗体 (AA 124-208)
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Quick Overview for SKAP2 抗体 (AA 124-208) (ABIN7870365)
抗原
See all SKAP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 124-208
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原理
- SKAP2 Antibody / PRAP / SCAP2
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids E124-E208) was used as the immunogen for the SKAP2 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the SKAP2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the SKAP2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- SKAP2 (Src Kinase Associated Phosphoprotein 2 (SKAP2))
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别名
- SKAP2
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背景
- Src kinase-associated phosphoprotein 2 is an enzyme that in humans is encoded by the SKAP2 gene. The protein encoded by this gene shares homology with Src kinase-associated phosphoprotein 1, and is a substrate of Src family kinases. It is an adaptor protein that is thought to play an essential role in the Src signaling pathway, and in regulating proper activation of the immune system. This protein contains an amino terminal coiled-coil domain for self-dimerization, a plecskstrin homology (PH) domain required for interactions with lipids at the membrane, and a Src homology (SH3) domain at the carboxy terminus. Some reports indicate that this protein inhibits actin polymerization through interactions with actin assembly factors, and might negatively regulate the invasiveness of tumors by modulating actin assembly. Alternative splicing results in multiple transcript variants encoding different isoforms.
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UniProt
- O75563
抗原
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