IMPDH1 抗体 (AA 123-500)
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Quick Overview for IMPDH1 抗体 (AA 123-500) (ABIN7870357)
抗原
See all IMPDH1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 123-500
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原理
- IMPDH1 Antibody / IMP dehydrogenase 1
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids P123-E500) was used as the immunogen for the IMPDH1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the IMPDH1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the IMPDH1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- IMPDH1 (Inosine 5'-Phosphate Dehydrogenase 1 (IMPDH1))
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别名
- IMPDH1
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背景
- Inosine-5'-monophosphate dehydrogenase 1, also known as IMP dehydrogenase 1, is an enzyme that in humans is encoded by the IMPDH1 gene. The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene.
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UniProt
- P20839
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途径
- Ribonucleoside Biosynthetic Process
抗原
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