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Recombinant MUC16 抗体 (AA 12201-12300)

The 兔 单克隆 anti-MUC16 antibody is suitable to detect MUC16 in samples from 人. It has been validated for IHC (p).
产品编号 ABIN7870341
发货至: 中国
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Quick Overview for Recombinant MUC16 抗体 (AA 12201-12300) (ABIN7870341)

抗原

See all MUC16 (CA125) 抗体
MUC16 (CA125) (Mucin 16, Cell Surface Associated (CA125))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

  • 126
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单克隆

标记

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This MUC16 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

OCA125-4505R
  • 抗原表位

    • 5
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    AA 12201-12300

    原理

    Recombinant MUC16 Antibody / CA125 (azide and preservative free)

    纯化方法

    Protein A affinity chromatography

    免疫原

    A portion of amino acids 12201-12300 from the human protein was used as the immunogen for the recombinant MUC16 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the recombinant MUC16 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    Store the recombinant MUC16 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • 抗原

    MUC16 (CA125) (Mucin 16, Cell Surface Associated (CA125))

    别名

    MUC16

    背景

    CA125 also known as mucin 16, is a member of the mucin family glycoproteins. CA125 is a component of the ocular surface (including the cornea and conjunctiva), the respiratory tract and the female reproductive tract epithelia. Since CA125 is highly glycosylated it creates a hydrophilic environment that acts as a lubricating barrier against foreign particles and infectious agents on the apical membrane of epithelial cells. CA125 reacts with both normal tissues and neoplasms of fallopian tube, endometrium, endocervix and mesothelioma. It does not react with colon cancer. Normal tissues such as breast, liver, skin, kidney and spleen are also negative. Studies have shown that CA125 reacts with approximately 80 % of epithelial ovarian neoplasms of serous, endometrioid, clear cell and undifferentiated types. No reactivity has been shown for mucinous ovarian tumors or in germ cell or hematopoietic tumors. This antibody is a useful aid for classification of a variety of tumors, such as some adenocarcinomas of the colon, breast carcinomas, malignant mesothelioma, uterine adenomatoid tumor, lung bronchoalveolar carcinoma, and ovarian endometrioid and serous carcinomas.

    UniProt

    Q8WXI7
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