CPT1A 抗体 (AA 122-556)
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Quick Overview for CPT1A 抗体 (AA 122-556) (ABIN7870339)
抗原
See all CPT1A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 122-556
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原理
- CPT1-L Antibody / CPT1A
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids M122-K556) was used as the immunogen for the CPT1-L antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the CPT1-L antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the CPT1-L antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- CPT1A (Carnitine Palmitoyltransferase 1A (Liver) (CPT1A))
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别名
- CPT1-L
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背景
- The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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UniProt
- P50416
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途径
- AMPK Signaling, Regulation of Lipid Metabolism by PPARalpha, Feeding Behaviour, Monocarboxylic Acid Catabolic Process
抗原
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