电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

BCL10 抗体 (AA 122-168)

This 小鼠 单克隆 antibody specifically detects BCL10 in IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN7870331
发货至: 中国
Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for BCL10 抗体 (AA 122-168) (ABIN7870331)

抗原

See all BCL10 抗体
BCL10 (B-Cell CLL/lymphoma 10 (BCL10))

适用

  • 175
  • 50
  • 24
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1

宿主

  • 129
  • 47
小鼠

克隆类型

  • 102
  • 75
单克隆

标记

  • 75
  • 12
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This BCL10 antibody is un-conjugated

应用范围

  • 116
  • 75
  • 71
  • 51
  • 43
  • 32
  • 31
  • 29
  • 18
  • 14
  • 13
  • 7
  • 3
  • 2
  • 1
  • 1
  • 1
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

SPM520
  • 抗原表位

    • 41
    • 16
    • 15
    • 8
    • 8
    • 7
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 122-168

    原理

    Bcl10 Antibody

    纯化方法

    Protein G affinity chromatography

    免疫原

    Amino acids 122-168 were used as the immunogen for this Bcl10 antibody.

    亚型

    IgG1, kappa
  • 应用备注

    The optimal dilution of the Bcl10 antibody for each application should be determined by the researcher.

    1. Staining of formalin-fixed tissues requires boiling tissue sections in pH 9 10 mM Tris with 1 mM EDTA for 10-20 min followed by cooling at RT for 20 minutes.
    2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide, *For IHC use only*

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store the Bcl10 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • 抗原

    BCL10 (B-Cell CLL/lymphoma 10 (BCL10))

    别名

    Bcl10

    背景

    Bcl10, with an N-terminal caspase recruitment domain (CARD), is found in a number of apoptotic regulatory molecules. It was identified through its direct involvement in t(1,14) of mucosa-associated lymphoid tissue (MALT) lymphoma. Expression of Bcl10 was shown to induce NF-kB activation in a NIK-dependent pathway. This mAb labels subpopulations of normal B and T cells and is a useful tool for the sub-classification of lymphomas. In MALT lymphomas with the t(1,14) translocation, while 55 % of MALT lymphomas lacking this translocation exhibited the same labeling pattern, although at a much lower level.

    UniProt

    O95999

    途径

    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins
You are here: