Utrophin 抗体 (AA 1211-2294)
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Quick Overview for Utrophin 抗体 (AA 1211-2294) (ABIN7870323)
抗原
See all Utrophin (UTRN) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1211-2294
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原理
- Utrophin Antibody / UTRN
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids L1211-K2294) was used as the immunogen for the Utrophin antibody.
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亚型
- IgG
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anti-Utrophin (UTRN) (AA 1-252) antibody
UTRN 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Utrophin (UTRN) (AA 3328-3433) antibodyUTRN 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 5G6 unconjugated
anti-Utrophin (UTRN) antibodyUTRN 适用: 人 IHC 宿主: 小鼠 Monoclonal DRP3-20C5 unconjugated
anti-Utrophin (UTRN) (AA 3328-3433) antibodyUTRN 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Optimal dilution of the Utrophin antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Utrophin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- Utrophin (UTRN)
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别名
- Utrophin
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背景
- Utrophin is a protein that in humans is encoded by the UTRN gene. This gene shares both structural and functional similarities with the dystrophin gene. It contains an actin-binding N-terminus, a triple coiled-coil repeat central region, and a C-terminus that consists of protein-protein interaction motifs which interact with dystroglycan protein components. The protein encoded by this gene is located at the neuromuscular synapse and myotendinous junctions, where it participates in post-synaptic membrane maintenance and acetylcholine receptor clustering. Mouse studies suggest that this gene may serve as a functional substitute for the dystrophin gene and therefore, may serve as a potential therapeutic alternative to muscular dystrophy which is caused by mutations in the dystrophin gene. Alternative splicing of the utrophin gene has been described, however, the full-length nature of these variants has not yet been determined.
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UniProt
- P46939
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途径
- Skeletal Muscle Fiber Development
抗原
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