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E2F5 抗体 (AA 121-346)

This 兔 多克隆 antibody specifically detects E2F5 in WB, ELISA 和 FACS. It exhibits reactivity toward 人.
产品编号 ABIN7870319
发货至: 中国
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Quick Overview for E2F5 抗体 (AA 121-346) (ABIN7870319)

抗原

See all E2F5 抗体
E2F5

适用

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宿主

  • 34
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克隆类型

  • 34
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多克隆

标记

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This E2F5 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Flow Cytometry (FACS)
  • 抗原表位

    • 8
    • 4
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    • 1
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    AA 121-346

    原理

    E2F5 Antibody

    纯化方法

    Antigen affinity purified

    免疫原

    Recombinant human E2F5 protein (amino acids C121-Y346) was used as the immunogen for the E2F5 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the E2F5 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the E2F5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    E2F5

    别名

    E2F5

    背景

    Transcription factor E2F5 is a protein that in humans is encoded by the E2F5 gene. The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionarily conserved domains that are present in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein is differentially phosphorylated and is expressed in a wide variety of human tissues. It has higher identity to E2F4 than to other family members. Both this protein and E2F4 interact with tumor suppressor proteins p130 and p107, but not with pRB. Alternative splicing results in multiple variants encoding different isoforms.

    UniProt

    Q15329
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