CENPI 抗体 (AA 120-604)
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Quick Overview for CENPI 抗体 (AA 120-604) (ABIN7870314)
抗原
See all CENPI 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 120-604
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原理
- CENPI Antibody / Centromere protein I
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human CENPI protein (amino acids K120-C604) was used as the immunogen for the CENPI antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the CENPI antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the CENPI antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- CENPI (Centromere Protein I (CENPI))
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别名
- CENPI
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背景
- Centromere protein I is a protein that in humans is encoded by the CENPI gene. This gene encodes a centromere protein that is a component of the CENPA-NAC (nucleosome-associated) complex. This complex is critical for accurate chromosome alignment and segregation and it ensures proper mitotic progression. This protein regulates the recruitment of kinetochore-associated proteins that are required to generate the spindle checkpoint signal. The product of this gene is involved in the response of gonadal tissues to follicle-stimulating hormone. Mutations in this gene may be involved in human X-linked disorders of gonadal development and gametogenesis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 13.
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UniProt
- Q92674
抗原
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