HDC 抗体 (AA 12-662)
Our Local Distributor
北京 101111
Quick Overview for HDC 抗体 (AA 12-662) (ABIN7870302)
抗原
See all HDC 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 12-662
-
原理
- Histidine decarboxylase Antibody / HDC
-
纯化方法
- Antigen affinity purified
-
免疫原
- Recombinant human protein (amino acids R12-V662) was used as the immunogen for the Histidine decarboxylase antibody.
-
亚型
- IgG
-
-
anti-Histidine Decarboxylase (HDC) (AA 160-369) antibody
HDC 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Histidine Decarboxylase (HDC) (Internal Region) antibodyHDC 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Histidine Decarboxylase (HDC) (AA 341-597) antibodyHDC 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Histidine Decarboxylase (HDC) (AA 504-648) antibodyHDC 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Histidine Decarboxylase (HDC) (AA 351-450) antibodyHDC 适用: 人, 小鼠 ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Histidine Decarboxylase (HDC) (AA 365-643) antibodyHDC 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Histidine Decarboxylase (HDC) (AA 449-462) antibodyVerified HDC 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Histidine Decarboxylase (HDC) (AA 147-178) antibodyHDC 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal dilution of the Histidine decarboxylase antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
-
储存条件
- 4 °C,-20 °C
-
储存方法
- After reconstitution, the Histidine decarboxylase antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
-
-
- HDC (Histidine Decarboxylase (HDC))
-
别名
- Histidine decarboxylase
-
背景
- HDC (Histidine decarboxylase) is the enzyme that catalyzes the reaction that produces histamine from histidine with the help of vitamin B6. The HDC gene is mapped on 15q21.2. The deduced 662-amino acid protein has a molecular mass of 74,148 Da. The gene contains 12 exons spanning approximately 24 kb. The biogenic amine histamine is an important modulator of numerous physiologic processes, including neurotransmission, gastric acid secretion, and smooth muscle tone. The biosynthesis of histamine from histidine is catalyzed by the enzyme L-histidine decarboxylase. This homodimeric enzyme is a pyridoxal phosphate(PLP)-dependent decarboxylase and is highly specific for its histidine substrate. Ercan-Sencicek et al. noted that animal studies had shown that lack of Hdc in mice results in increased locomotor and stereotypic behaviors, as well as increased anxiety.
-
UniProt
- P19113
抗原
-
