TRIM21 抗体 (AA 12-475)
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Quick Overview for TRIM21 抗体 (AA 12-475) (ABIN7870296)
抗原
See all TRIM21 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 12-475
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原理
- SS-A Antibody / TRIM21
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纯化方法
- Affinity purified
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免疫原
- Recombinant human protein (amino acids E12-Y475) was used as the immunogen for the SS-A antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the SS-A antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the SS-A antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- TRIM21 (Tripartite Motif Containing 21 (TRIM21))
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别名
- SS-A
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背景
- Tripartite motif-containing protein 21 also known as E3 ubiquitin-protein ligase TRIM21 is a protein that in humans is encoded by the TRIM21 gene. It is mapped to 11p15.4. This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined.
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UniProt
- P19474
抗原
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