STRADA 抗体 (AA 12-41)
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Quick Overview for STRADA 抗体 (AA 12-41) (ABIN7870293)
抗原
See all STRADA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 12-41
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原理
- LYK5 Antibody / STRADA
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 12-41 from the human protein was used as the immunogen for the LYK5 antibody.
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亚型
- Ig Fraction
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anti-STE20-Related Kinase Adaptor alpha (STRADA) (AA 303-346), (C-Term) antibody
STRADA 适用: 人, 小鼠 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB47810 unconjugated
anti-STE20-Related Kinase Adaptor alpha (STRADA) (AA 251-346) antibodySTRADA 适用: 人 WB, ELISA, IHC (p), PLA 宿主: 小鼠 Monoclonal 4E4 unconjugated
anti-STE20-Related Kinase Adaptor alpha (STRADA) (AA 12-41), (N-Term) antibodySTRADA 适用: 人 WB, IF, FACS 宿主: 兔 Polyclonal RB8539 unconjugated
anti-STE20-Related Kinase Adaptor alpha (STRADA) antibodySTRADA 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-STE20-Related Kinase Adaptor alpha (STRADA) (AA 1-348) antibodySTRADA 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-STE20-Related Kinase Adaptor alpha (STRADA) (AA 25-210) antibodySTRADA 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-STE20-Related Kinase Adaptor alpha (STRADA) (Internal Region) antibodySTRADA 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-STE20-Related Kinase Adaptor alpha (STRADA) (Internal Region) antibodySTRADA 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-STE20-Related Kinase Adaptor alpha (STRADA) (AA 25-210) antibodySTRADA 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-STE20-Related Kinase Adaptor alpha (STRADA) (N-Term) antibodySTRADA 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- The stated application concentrations are suggested starting points. Titration of the LYK5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the LYK5 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- STRADA (STE20-Related Kinase Adaptor alpha (STRADA))
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别名
- LYK5
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背景
- LYK5, also STE20-related Adaptor Protein (STRAD) are members of STE-20 like kinase family that are known to stimulate MAPK pathways by directly activating MAPKKK. LYK5 is a novel pseudokinase member of this family consisting of a STE-20 like kinase domain but lacks several residues that are required for its catalytic activity. It specifically binds LKB1 and plays a key role in regulating tumor suppressor activities of LKB1. It functions as an upstream activator of LKB1 and also directs the sub-cellular localization of LKB1 by anchoring it in the cytoplasm. STRAD-LKB1 interaction results in phosphorylation of STRAD and enhanced autophosphorylation of LKB1.
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UniProt
- Q7RTN6
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途径
- AMPK Signaling
抗原
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