PFKFB1 抗体 (AA 12-186)
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Quick Overview for PFKFB1 抗体 (AA 12-186) (ABIN7870283)
抗原
See all PFKFB1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 12-186
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原理
- PFKFB1 Antibody / Fructose-2,6-bisphosphatase
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纯化方法
- Antigen affinity purified
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免疫原
- E. coli-derived recombinant human protein (amino acids R12-R186) was used as the immunogen for the PFKFB1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the PFKFB1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the PFKFB1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- PFKFB1 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1))
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别名
- PFKFB1
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背景
- 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 is an enzyme that in humans is encoded by the PFKFB1 gene. This gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis. Multiple alternatively spliced transcript variants have been found for this gene.
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UniProt
- P16118
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途径
- Regulation of Carbohydrate Metabolic Process
抗原
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