PCDHa8 抗体 (AA 118-801)
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Quick Overview for PCDHa8 抗体 (AA 118-801) (ABIN7870268)
抗原
See all PCDHa8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 118-801
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原理
- PCDHA8 Antibody / Protocadherin alpha-8
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纯化方法
- Antigen affinity purified
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免疫原
- An E.coli-derived human recombinant protein (amino acids H118-Q801) was used as the immunogen for the PCDHA8 antibody.
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亚型
- IgG
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anti-Protocadherin alpha 8 (PCDHa8) (AA 773-800), (C-Term) antibody
PCDHa8 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB31684 unconjugated
anti-Protocadherin alpha 8 (PCDHa8) (AA 719-922) antibodyPCDHa8 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protocadherin alpha 8 (PCDHa8) (AA 780-808), (C-Term) antibodyPCDHa8 适用: 人 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the PCDHA8 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the PCDHA8 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- PCDHa8 (Protocadherin alpha 8 (PCDHa8))
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别名
- PCDHA8
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背景
- This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.
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UniProt
- Q9Y5H6
抗原
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