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ISL1 抗体 (AA 118-161)

The 兔 多克隆 anti-ISL1 antibody is suitable to detect ISL1 in samples from 人, 小鼠 和 大鼠. It has been validated for WB, ELISA, IF 和 IHC (p).
产品编号 ABIN7870257
发货至: 中国
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Quick Overview for ISL1 抗体 (AA 118-161) (ABIN7870257)

抗原

See all ISL1 抗体
ISL1 (ISL LIM Homeobox 1 (ISL1))

适用

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人, 小鼠, 大鼠

宿主

  • 98
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克隆类型

  • 65
  • 42
多克隆

标记

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This ISL1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 15
    • 9
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    AA 118-161

    原理

    Islet 1 Antibody / ISL1

    纯化方法

    Antigen affinity chromatography

    免疫原

    An E.coli-derived human recombinant protein (amino acids D118-E161) was used as the immunogen for the Islet 1 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the Islet 1 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the Islet 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    ISL1 (ISL LIM Homeobox 1 (ISL1))

    别名

    Islet 1

    背景

    Insulin gene enhancer protein ISL-1 is a protein that in humans is encoded by the isl1 gene. This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young.

    UniProt

    P61371

    途径

    Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding
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