ISL1 抗体 (AA 118-161)
Our Local Distributor
北京 101111
Quick Overview for ISL1 抗体 (AA 118-161) (ABIN7870257)
抗原
See all ISL1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 118-161
-
原理
- Islet 1 Antibody / ISL1
-
纯化方法
- Antigen affinity chromatography
-
免疫原
- An E.coli-derived human recombinant protein (amino acids D118-E161) was used as the immunogen for the Islet 1 antibody.
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal dilution of the Islet 1 antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
-
储存条件
- 4 °C,-20 °C
-
储存方法
- After reconstitution, the Islet 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
-
-
- ISL1 (ISL LIM Homeobox 1 (ISL1))
-
别名
- Islet 1
-
背景
- Insulin gene enhancer protein ISL-1 is a protein that in humans is encoded by the isl1 gene. This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young.
-
UniProt
- P61371
-
途径
- Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding
抗原
-