TJP1 抗体 (AA 1178-1527)
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Quick Overview for TJP1 抗体 (AA 1178-1527) (ABIN7870254)
抗原
See all TJP1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1178-1527
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原理
- TJP1 Antibody / ZO-1
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纯化方法
- Affinity purified
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免疫原
- A human recombinant protein (amino acids H1178-F1527) was used as the immunogen for the TJP1 antibody.
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亚型
- IgG1
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应用备注
- Optimal dilution of the TJP1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the TJP1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- TJP1 (Tight Junction Protein 1 (TJP1))
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别名
- TJP1
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背景
- Tight junction protein ZO-1 is a protein that in humans is encoded by the TJP1 gene. It is mapped to 15q13.1. This gene encodes a protein located on a cytoplasmic membrane surface of intercellular tight junctions. The encoded protein may be involved in signal transduction at cell-cell junctions. It has been found that injected CagA associates with the epithelial tight-junction scaffolding protein TJP1 and the transmembrane protein junctional adhesion molecule, causing an ectopic assembly of tight junction components at sites of bacterial attachment, and altering the composition and function of the apical-junctional complex.
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UniProt
- Q07157
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途径
- Carbohydrate Homeostasis, Cell-Cell Junction Organization
抗原
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