PDIA2 抗体 (AA 117-492)
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Quick Overview for PDIA2 抗体 (AA 117-492) (ABIN7870250)
抗原
See all PDIA2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 117-492
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原理
- PDIA2 Antibody / Protein disulfide-isomerase A2 / PDIp
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids Y117-D492) was used as the immunogen for the PDIA2 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the PDIA2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the PDIA2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- PDIA2 (Protein Disulfide Isomerase Family A, Member 2 (PDIA2))
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别名
- PDIA2
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背景
- Protein disulfide isomerase family A member 2 is a protein that in humans is encoded by the PDIA2 gene. This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, two catalytically active thioredoxin (TRX) domains, two TRX-like domains and a C-terminal ER-retention sequence. The protein plays a role in the folding of nascent proteins in the endoplasmic reticulum by forming disulfide bonds through its thiol isomerase, oxidase, and reductase activity. The encoded protein also possesses estradiol-binding activity and can modulate intracellular estradiol levels.
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UniProt
- Q13087
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途径
- Maintenance of Protein Location, Cell RedoxHomeostasis, Unfolded Protein Response
抗原
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