Mast Cell Tryptase 抗体 (AA 115-233)
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Quick Overview for Mast Cell Tryptase 抗体 (AA 115-233) (ABIN7870202)
抗原
See all Mast Cell Tryptase 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 115-233
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原理
- Mast Cell Tryptase Antibody / TPSAB1
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纯化方法
- Protein G affinity chromatography
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免疫原
- A portion of amino acids 115-233 from the human protein was used as the immunogen for this TPSAB1 antibody.
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亚型
- IgG1, kappa
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anti-Mast Cell Tryptase antibody
Carrier-free 适用: 人, 大鼠, Cat, 犬, 猴 WB, IHC (p), ELISA, IF, IHC (fro) 宿主: 小鼠 Monoclonal AA1 unconjugated
anti-Mast Cell Tryptase antibody适用: 人 IHC, IHC (p) 宿主: 小鼠 Monoclonal 10D11 unconjugated
anti-Mast Cell Tryptase antibody适用: 人 WB, IHC (p), ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the Mast Cell Tryptase antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the Mast Cell Tryptase antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- Mast Cell Tryptase
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背景
- Tryptases comprise a family of trypsin-like serine proteases (peptidase family S1). Tryptases are stored in mast cell secretory granules and basophils. Mast cells are connective tissue cells derived from blood-forming tissues that line arterial walls and secrete substances, which mediate inflammatory and immune responses. Tryptases are released into the extracellular environment and are resistant to all known endogenous proteinase inhibitors. This antibody reacts with mast cells distributed in skin, synovium, lung, and heart. This antibody does not bind with any other cell type. Human mast cell tryptase is considered to be an important marker of mast cell activation and is an important mediator of inflammation. Mastocytosis is a term collectively used for a group of disorders in which there is abnormal accumulation of mast cells in one or multiple organs. Anti-tryptase, combined with anti-CD2, anti-CD25, and anti-CD117, can be useful in identifying reactive mast cell hyperplasia, myelogenous neoplasms, mast cell leukemia, and mastocytosis.
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UniProt
- Q15661
抗原
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