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HOXB2 抗体 (AA 114-220)

The 小鼠 单克隆 anti-HOXB2 antibody is suitable to detect HOXB2 in samples from 人. It has been validated for WB, ELISA, IF, IHC (p) 和 FACS.
产品编号 ABIN7870167
发货至: 中国
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Quick Overview for HOXB2 抗体 (AA 114-220) (ABIN7870167)

抗原

See all HOXB2 抗体
HOXB2 (Homeobox B2 (HOXB2))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This HOXB2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

质量等级

Carrier-free

克隆位点

PCRP-HOXB2-1F2
  • 抗原表位

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    AA 114-220

    原理

    HOXB2 Antibody (azide and preservative free)

    纯化方法

    Protein A/G affinity

    免疫原

    A portion of amino acids 114-220 was used as the immunogen for the HOXB2 antibody.

    亚型

    IgG2b
  • 应用备注

    Optimal dilution of the HOXB2 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    -20 °C

    储存方法

    Aliquot the HOXB2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    HOXB2 (Homeobox B2 (HOXB2))

    别名

    HOXB2

    背景

    Hox genes play a fundamental role in the development of the vertebrate central nervous system, heart, axial skeleton, limbs, gut, urogenital tract and external genitalia. The homeobox gene HoxB1 is critical to hindbrain development and has phenotypic features frequently observed in autism. Analysis of expression and targeted disruption of HoxB1 demonstrates that it is also essential for patterning progenitor cells along the entire DV axis of rhombomere 4 (r4). HoxB1 maintains this function by acting very early during hindbrain neurogenesis to specify effectors of the Sonic hedgehog and Mash1 signaling pathways. HoxB2 is a homeodomain protein important in neural development that is also expressed during erythropoiesis, hindbrain development and normal human adult lung development. HoxB2 may modulate the amount of gamma-globin mRNA expressed during development and differentiation. In addition, HoxB2 plays an important role in the patterning of hindbrain and pharyngeal arches in the zebrafish.

    UniProt

    P14652
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