IL3RA 抗体 (AA 111-378)
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Quick Overview for IL3RA 抗体 (AA 111-378) (ABIN7870120)
抗原
See all IL3RA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 111-378
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原理
- CD123 Antibody / IL3RA
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纯化方法
- Affinity purified
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免疫原
- Recombinant human protein (amino acids T111-T378) was used as the immunogen for the CD123 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the CD123 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the CD123 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- IL3RA (Interleukin 3 Receptor, alpha (IL3RA))
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别名
- CD123
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背景
- Interleukin 3 receptor, alpha (low affinity) (IL3RA), also known as CD123 (Cluster of Differentiation 123), is a human gene. It is mapped to Xp22.33 and Yp11.2. The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y. Alternatively spliced transcript variants encoding distinct isoforms have been found.
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UniProt
- P26951
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途径
- JAK/STAT Signaling
抗原
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