Cadherin 20 抗体 (AA 111-140)
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Quick Overview for Cadherin 20 抗体 (AA 111-140) (ABIN7870114)
抗原
See all Cadherin 20 (CDH20) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 111-140
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原理
- Cadherin 20 Antibody / CDH20
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 111-140 from the human protein was used as the immunogen for the Cadherin 20 antibody.
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亚型
- Ig Fraction
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应用备注
- The stated application concentrations are suggested starting points. Titration of the Cadherin 20 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Cadherin 20 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Cadherin 20 (CDH20)
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别名
- Cadherin 20
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背景
- This gene is a type II classical cadherin from the cadherin superfamily and one of three cadherin 7-like genes located in a cluster on chromosome 18. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Since disturbance of intracellular adhesion is a prerequisite for invasion and metastasis of tumor cells, cadherins are considered prime candidates for tumor suppressor genes.
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UniProt
- Q9HBT6
抗原
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