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RAP1GAP 抗体 (AA 11-661)

The 兔 多克隆 anti-RAP1GAP antibody (ABIN7870090) specifically detects RAP1GAP in WB, ELISA, IF, FACS 和 IHC (p). The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7870090
发货至: 中国
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Quick Overview for RAP1GAP 抗体 (AA 11-661) (ABIN7870090)

抗原

See all RAP1GAP 抗体
RAP1GAP (RAP1 GTPase Activating Protein (RAP1GAP))

适用

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人, 小鼠, 大鼠

宿主

  • 36
  • 11

克隆类型

  • 26
  • 21
多克隆

标记

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This RAP1GAP antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 5
    • 1
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    AA 11-661

    原理

    RAP1GAP Antibody / Rap1 GTPase-activating protein 1

    纯化方法

    Antigen affinity purified

    免疫原

    E. coli-derived recombinant human protein (amino acids D11-L661) was used as the immunogen for the RAP1GAP antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the RAP1GAP antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the RAP1GAP antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    RAP1GAP (RAP1 GTPase Activating Protein (RAP1GAP))

    别名

    RAP1GAP

    背景

    Rap1 GTPase-activating protein 1 is an enzyme that in humans is encoded by the RAP1GAP gene. This gene encodes a type of GTPase-activating-protein (GAP) that down-regulates the activity of the ras-related RAP1 protein. RAP1 acts as a molecular switch by cycling between an inactive GDP-bound form and an active GTP-bound form. The product of this gene, RAP1GAP, promotes the hydrolysis of bound GTP and hence returns RAP1 to the inactive state whereas other proteins, guanine nucleotide exchange factors (GEFs), act as RAP1 activators by facilitating the conversion of RAP1 from the GDP- to the GTP-bound form. In general, ras subfamily proteins, such as RAP1, play key roles in receptor-linked signaling pathways that control cell growth and differentiation. RAP1 plays a role in diverse processes such as cell proliferation, adhesion, differentiation, and embryogenesis. Alternative splicing results in multiple transcript variants encoding distinct proteins.

    UniProt

    P47736
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