PDE6A 抗体 (AA 11-237)
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Quick Overview for PDE6A 抗体 (AA 11-237) (ABIN7870070)
抗原
See all PDE6A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 11-237
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原理
- PDE6 alpha Antibody / PDE6A
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纯化方法
- Affinity purified
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免疫原
- Recombinant human protein (amino acids K11-R237) was used as the immunogen for the PDE6 alpha antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the PDE6 alpha antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the PDE6 alpha antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- PDE6A (phosphodiesterase 6A, CGMP-Specific, Rod, alpha (PDE6A))
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别名
- PDE6 alpha
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背景
- This gene encodes the cyclic-GMP (cGMP)-specific phosphodiesterase 6A alpha subunit, expressed in cells of the retinal rod outer segment. The phosphodiesterase 6 holoenzyme is a heterotrimer composed of an alpha, beta, and two gamma subunits. cGMP is an important regulator of rod cell membrane current, and its dynamic concentration is established by phosphodiesterase 6A cGMP hydrolysis and guanylate cyclase cGMP synthesis. The protein is a subunit of a key phototransduction enzyme and participates in processes of transmission and amplification of the visual signal. Mutations in this gene have been identified as one cause of autosomal recessive retinitis pigmentosa.
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UniProt
- P16499
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
抗原
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