TXNDC5 抗体 (AA 109-403)
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Quick Overview for TXNDC5 抗体 (AA 109-403) (ABIN7870056)
抗原
See all TXNDC5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 109-403
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原理
- TXNDC5 Antibody / Thioredoxin domain-containing protein 5
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纯化方法
- Antigen affinity purified
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免疫原
- E. coli-derived recombinant human protein (amino acids M109-R403) was used as the immunogen for the TXNDC5 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the TXNDC5 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the TXNDC5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- TXNDC5 (Thioredoxin Domain Containing 5 (Endoplasmic Reticulum) (TXNDC5))
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别名
- TXNDC5
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背景
- Thioredoxin domain-containing protein 5 is a protein that in humans is encoded by the TXNDC5 gene. This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal endoplasmic reticulum (ER)-signal sequence, three catalytically active thioredoxin domains and a C-terminal ER-retention sequence. Its expression is induced by hypoxia and its role may be to protect hypoxic cells from apoptosis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream BLOC1S5 gene.
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UniProt
- Q8NBS9
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途径
- Cell RedoxHomeostasis
抗原
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