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FLI1 抗体 (AA 107-261)

The 小鼠 单克隆 anti-FLI1 antibody (Clone FLI1-1312) (ABIN7870009) specifically detects FLI1 in WB, IF 和 FACS. The antibody is reactive with 人 samples.
产品编号 ABIN7870009
发货至: 中国
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Quick Overview for FLI1 抗体 (AA 107-261) (ABIN7870009)

抗原

See all FLI1 抗体
FLI1 (Friend Leukemia Virus Integration 1 (FLI1))

适用

  • 115
  • 48
  • 22
  • 9
  • 6
  • 6
  • 6
  • 6
  • 5
  • 5
  • 5
  • 4
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  • 4

宿主

  • 81
  • 34
  • 2
小鼠

克隆类型

  • 65
  • 52
单克隆

标记

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  • 6
  • 4
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  • 3
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  • 3
  • 3
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  • 2
  • 2
  • 1
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This FLI1 antibody is un-conjugated

应用范围

  • 91
  • 48
  • 33
  • 28
  • 18
  • 12
  • 10
  • 8
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

质量等级

Carrier-free

克隆位点

FLI1-1312
  • 抗原表位

    • 21
    • 9
    • 8
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 107-261

    原理

    FLI1 Antibody / Friend leukemia integration 1 transcription factor (azide and preservative free)

    纯化方法

    Protein A/G affinity

    免疫原

    A recombinant fragment (amino acids 107-261) of human FLI1 protein with hexa-histidine tag was used as the immunogen for the FLI1 antibody.

    亚型

    IgG1, kappa
  • 应用备注

    Optimal dilution of the FLI1 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    -20 °C

    储存方法

    Aliquot the FLI1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    FLI1 (Friend Leukemia Virus Integration 1 (FLI1))

    别名

    FLI1

    背景

    Recognizes a protein of 51 kDa, which is identified as FLI1. This protein, a member of the ETS family of DNA binding transcription factors, is involved in cellular proliferation and tumorigenesis. Ets-1 is the prototype member of a family of genes identified on the basis of homology to the v-Ets oncogene isolated from the E26 erythroblastosis virus.Members of the Ets gene family share a highly conserved carboxy-terminal domain containing a sequence related to the SV40 large T antigen nuclear localization signal sequence. Approximately 90 % of Ewing's Sarcoma (EWS) / Primitive Neuroectodermal Tumors (PNET) have a specific translocation, t(11,22)(q24,q12), which results in fusion of EWS to Fli-1, and production of an EWS-Fli-1 fusion protein. Among normal tissues only endothelial cells and small lymphocytes express Fli-1. This protein is expressed in majority of vascular tumors including angiosarcomas, hemangioendotheliomas, hemangiomas, and Kaposi's Sarcomas. High sensitivity and specificity of Fli-1 equals to or exceeds that of the established vascular markers like CD31, CD34, and Factor VIII.

    UniProt

    Q01543
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