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FOXL1 抗体 (AA 104-258)

The 小鼠 单克隆 anti-FOXL1 antibody (Clone PCRP-FOXL1-1F8) (ABIN7869967) specifically detects FOXL1 in WB, IHC (p), IF 和 FACS. The antibody is reactive with 人 samples.
产品编号 ABIN7869967
发货至: 中国
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Quick Overview for FOXL1 抗体 (AA 104-258) (ABIN7869967)

抗原

See all FOXL1 抗体
FOXL1 (Forkhead Box L1 (FOXL1))

适用

  • 44
  • 22
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1

宿主

  • 36
  • 8
小鼠

克隆类型

  • 37
  • 7
单克隆

标记

  • 32
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This FOXL1 antibody is un-conjugated

应用范围

  • 37
  • 22
  • 17
  • 7
  • 7
  • 3
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Flow Cytometry (FACS)

克隆位点

PCRP-FOXL1-1F8
  • 抗原表位

    • 8
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 104-258

    原理

    FOXL1 Antibody

    纯化方法

    Protein A/G affinity

    免疫原

    A portion of amino acids 104-258 was used as the immunogen for the FOXL1 antibody.

    亚型

    IgG1
  • 应用备注

    Optimal dilution of the FOXL1 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the FOXL1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    FOXL1 (Forkhead Box L1 (FOXL1))

    别名

    FOXL1

    背景

    FOXL1 is a 337 amino acid protein encoded by the mouse gene FOXL1. FOXL1 belongs to the forkhead family and contains one forkhead DNA-binding domain. The HNF3/forkhead family includes a large number of transcription factors that share a structurally related DNA binding domain. forkhead factors are known to play important roles both during development and in adults. FOXL1 is a winged helix transcriptional regulator expressed in the mesenchymal layer of developing and mature gastrointestinal tract. FOXL1-deficient mice exhibit various defects not only in the epithelial layer of the gastrointestinal tract but also in gut-associated lymphoid tissues. In the small intestine of FOXL1-deficient mice, the formation of Peyers patches is affected, particularly in the caudal region. FOXL1 is a mesenchymal modifier of the Adenomatous Polyposis Coli (APC) gene products and plays a key role in gastrointestinal tumorigenesis.

    UniProt

    Q12951
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