FOXL1 抗体 (AA 104-258)
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Quick Overview for FOXL1 抗体 (AA 104-258) (ABIN7869966)
抗原
See all FOXL1 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- AA 104-258
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原理
- FOXL1 Antibody (azide and preservative free)
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纯化方法
- Protein A/G affinity
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免疫原
- A portion of amino acids 104-258 was used as the immunogen for the FOXL1 antibody.
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亚型
- IgG1
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应用备注
- Optimal dilution of the FOXL1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Aliquot the FOXL1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- FOXL1 (Forkhead Box L1 (FOXL1))
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别名
- FOXL1
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背景
- FOXL1 is a 337 amino acid protein encoded by the mouse gene FOXL1. FOXL1 belongs to the forkhead family and contains one forkhead DNA-binding domain. The HNF3/forkhead family includes a large number of transcription factors that share a structurally related DNA binding domain. forkhead factors are known to play important roles both during development and in adults. FOXL1 is a winged helix transcriptional regulator expressed in the mesenchymal layer of developing and mature gastrointestinal tract. FOXL1-deficient mice exhibit various defects not only in the epithelial layer of the gastrointestinal tract but also in gut-associated lymphoid tissues. In the small intestine of FOXL1-deficient mice, the formation of Peyers patches is affected, particularly in the caudal region. FOXL1 is a mesenchymal modifier of the Adenomatous Polyposis Coli (APC) gene products and plays a key role in gastrointestinal tumorigenesis.
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UniProt
- Q12951
抗原
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