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FOXL1 抗体 (AA 104-258)

The 小鼠 单克隆 anti-FOXL1 antibody is suitable to detect FOXL1 in samples from 人. It has been validated for WB, IHC (p), IF 和 FACS.
产品编号 ABIN7869966
发货至: 中国
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Quick Overview for FOXL1 抗体 (AA 104-258) (ABIN7869966)

抗原

See all FOXL1 抗体
FOXL1 (Forkhead Box L1 (FOXL1))

适用

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宿主

  • 36
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小鼠

克隆类型

  • 37
  • 7
单克隆

标记

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This FOXL1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Flow Cytometry (FACS)

质量等级

Carrier-free

克隆位点

PCRP-FOXL1-1F8
  • 抗原表位

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    AA 104-258

    原理

    FOXL1 Antibody (azide and preservative free)

    纯化方法

    Protein A/G affinity

    免疫原

    A portion of amino acids 104-258 was used as the immunogen for the FOXL1 antibody.

    亚型

    IgG1
  • 应用备注

    Optimal dilution of the FOXL1 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    -20 °C

    储存方法

    Aliquot the FOXL1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    FOXL1 (Forkhead Box L1 (FOXL1))

    别名

    FOXL1

    背景

    FOXL1 is a 337 amino acid protein encoded by the mouse gene FOXL1. FOXL1 belongs to the forkhead family and contains one forkhead DNA-binding domain. The HNF3/forkhead family includes a large number of transcription factors that share a structurally related DNA binding domain. forkhead factors are known to play important roles both during development and in adults. FOXL1 is a winged helix transcriptional regulator expressed in the mesenchymal layer of developing and mature gastrointestinal tract. FOXL1-deficient mice exhibit various defects not only in the epithelial layer of the gastrointestinal tract but also in gut-associated lymphoid tissues. In the small intestine of FOXL1-deficient mice, the formation of Peyers patches is affected, particularly in the caudal region. FOXL1 is a mesenchymal modifier of the Adenomatous Polyposis Coli (APC) gene products and plays a key role in gastrointestinal tumorigenesis.

    UniProt

    Q12951
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