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Cathepsin D 抗体 (AA 104-250)

The 小鼠 单克隆 anti-Cathepsin D antibody is suitable to detect Cathepsin D in samples from 人. It has been validated for WB, IF 和 IHC (p).
产品编号 ABIN7869957
发货至: 中国
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Quick Overview for Cathepsin D 抗体 (AA 104-250) (ABIN7869957)

抗原

See all Cathepsin D (CTSD) 抗体
Cathepsin D (CTSD)

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Cathepsin D antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

CTSD-3276
  • 抗原表位

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    AA 104-250

    原理

    Cathepsin D Antibody

    纯化方法

    Protein G affinity chromatography

    免疫原

    A recombinant human partial protein (amino acids 104-250) was used as the immunogen of the Cathepsin D antibody.

    亚型

    IgG2b, kappa
  • 应用备注

    Optimal dilution of the Cathepsin D antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store the Cathepsin D antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • 抗原

    Cathepsin D (CTSD)

    别名

    Cathepsin D

    背景

    Cathepsin D is a ubiquitously expressed lysosomal aspartyl protease involved in the normal degradation of proteins. It is synthesized as an inactive 52 kDa preprocathepsin D that is cleaved and glycosylated to form a 48 kDa procathepsin D and then further cleaved to produce 34 kDa and 14 kDa subunits (heavy and light chains, respectively). Cathepsin D exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease.

    UniProt

    P07339

    途径

    Peptide Hormone Metabolism
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