CBS 抗体 (AA 102-342)
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Quick Overview for CBS 抗体 (AA 102-342) (ABIN7869914)
抗原
See all CBS 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 102-342
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原理
- CBS Antibody / Cystathionine Beta Synthase
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids K102-E342) was used as the immunogen for the CBS antibody.
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亚型
- IgG1
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应用备注
- Optimal dilution of the CBS antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the CBS antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- CBS (Cystathionine-beta-Synthase (CBS))
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别名
- CBS
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背景
- CBS, Cystathionine Beta-Synthase, catalyzes the first irreversible step of transsulfuration. The CBS enzyme is a homotetramer of 63-kD subunits and requires pyridoxal phosphate and heme for activity. The CBS gene, which is mapped to chromosome 21q22, contains 23 exons, ranging in size from 42 to 299 bp. The human CBS protein can substitute for the endogenous yeast CBS protein in Saccharomyces cerevisiae. The catalytic domain of the CBS protein is located in the N-terminal 409 amino acids, and a regulatory domain is located in the C-terminal 142 amino acids.A mutation that deletes the C-terminal 145 amino acids of CBS could restore activity of several CBS mutant alleles found in homocystinurics.
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UniProt
- P35520
抗原
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