CBS 抗体 (AA 102-342)
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北京 101111
Quick Overview for CBS 抗体 (AA 102-342) (ABIN7869913)
抗原
See all CBS 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 102-342
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原理
- CBS Antibody / Cystathionine Beta Synthase
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纯化方法
- Antigen affinity purified
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免疫原
- A human recombinant partial protein (amino acids K102-E342) was used as the immunogen for the CBS antibody.
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亚型
- IgG
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anti-Cystathionine-beta-Synthase (CBS) (AA 1-100) antibody
CBS 适用: 人 WB, ELISA, IHC (p), IP, RNAi 宿主: 小鼠 Monoclonal 3E1 unconjugated
anti-Cystathionine-beta-Synthase (CBS) (AA 252-551) antibodyCBS 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Cystathionine-beta-Synthase (CBS) (AA 104-133), (N-Term) antibodyCBS 适用: 人, 小鼠 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB22961 unconjugated
anti-Cystathionine-beta-Synthase (CBS) (AA 1-100) antibodyCBS 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 6A9 unconjugated
anti-Cystathionine-beta-Synthase (CBS) antibodyKD Validated CBS 适用: 人 WB, FACS, IF (p) 宿主: 兔 Monoclonal 23GB3800 unconjugated Recombinant Antibody
anti-Cystathionine-beta-Synthase (CBS) (AA 301-330) antibodyCBS 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB21183 unconjugated
anti-Cystathionine-beta-Synthase (CBS) (N-Term) antibodyCBS 适用: 人, 小鼠, 大鼠, 犬, 斑马鱼, Cow, 豚鼠, 马, 兔, Saccharomyces cerevisiae WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cystathionine-beta-Synthase (CBS) (AA 1-413) antibodyCBS 适用: 人 WB, ELISA, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Cystathionine-beta-Synthase (CBS) antibodyCBS 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Cystathionine-beta-Synthase (CBS) antibodyKO Validated CBS 适用: 人 WB, IF, IHC (p), ICC, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the CBS antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the CBS antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- CBS (Cystathionine-beta-Synthase (CBS))
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别名
- CBS
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背景
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CBS (Cystathionine Beta Synthase) is a pyridoxal-5'-phosphate-dependent enzyme that plays a central role in the transsulfuration pathway. It catalyzes the condensation of serine and homocysteine to form cystathionine, an essential step in the synthesis of cysteine. This pathway is critical for maintaining sulfur amino acid metabolism, redox balance, and cellular homeostasis. A CBS antibody is commonly used in research focused on amino acid metabolism and associated disorders.
In addition to its role in cysteine biosynthesis, CBS activity contributes to the regulation of homocysteine levels. Elevated homocysteine is a known risk factor for cardiovascular disease, stroke, and neurodegeneration. Mutations in the CBS gene are responsible for homocystinuria, a metabolic disorder characterized by abnormal accumulation of homocysteine, highlighting the enzyme’s clinical significance. Researchers employ a CBS antibody to study enzyme expression and function in metabolic pathways and disease models.
CBS is also involved in producing hydrogen sulfide (H2S), a gaseous signaling molecule with important roles in vascular function, neuromodulation, and cytoprotection. Dysregulated H2S production has been associated with cancer, hypertension, and neurological disease. Investigating CBS with a CBS antibody allows researchers to better understand its enzymatic versatility and its impact on multiple signaling networks.
NSJ Bioreagents offers a high-quality CBS antibody validated for applications such as western blot, immunohistochemistry, and immunoprecipitation. Selecting a CBS antibody from NSJ Bioreagents ensures reliable detection and reproducible results in studies of sulfur metabolism, homocysteine regulation, and disease biology.
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UniProt
- P35520
抗原
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