SEC31A 抗体 (AA 101-806)
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北京 101111
Quick Overview for SEC31A 抗体 (AA 101-806) (ABIN7869901)
抗原
See all SEC31A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 101-806
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原理
- SEC31A Antibody
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纯化方法
- Antigen affinity purified
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免疫原
- E. coli-derived recombinant human protein (amino acids Y101-K806) was used as the immunogen for the SEC31A antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the SEC31A antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the SEC31A antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- SEC31A (SEC31 Homolog A (SEC31A))
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别名
- SEC31A
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背景
- Protein transport protein Sec31A is a protein that in humans is encoded by the SEC31A gene. The protein encoded by this gene shares similarity with the yeast Sec31 protein, and is a component of the outer layer of the coat protein complex II (COPII). The encoded protein is involved in vesicle budding from the endoplasmic reticulum (ER) and contains multiple WD repeats near the N-terminus and a proline-rich region in the C-terminal half. It associates with the protein encoded by the SEC13 homolog, nuclear pore and COPII coat complex component (SEC13), and is required for ER-Golgi transport. Monoubiquitylation of this protein by CUL3-KLHL12 was found to regulate the size of COPII coats to accommodate unusually shaped cargo. Alternative splicing results in multiple transcript variants encoding different isoforms.
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UniProt
- O94979
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途径
- ER-Nucleus Signaling
抗原
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