MTDH 抗体 (AA 101-270)
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北京 101111
Quick Overview for MTDH 抗体 (AA 101-270) (ABIN7869896)
抗原
See all MTDH 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 101-270
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原理
- AEG-1 Antibody / Astrocyte elevated gene-1 / MTDH / LYRIC
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids D101-Q270) was used as the immunogen for the AEG-1 antibody.
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亚型
- IgG2b
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anti-Metadherin (MTDH) antibody
MTDH 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Metadherin (MTDH) (AA 101-270) antibodyMTDH 适用: 人, 小鼠, 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Metadherin (MTDH) antibodyMTDH 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Metadherin (MTDH) (AA 1-582) antibodyMTDH 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Metadherin (MTDH) (AA 1-582) antibodyMTDH 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Metadherin (MTDH) antibodyMTDH 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 2F11C3 unconjugated
anti-Metadherin (MTDH) (AA 1-260) antibodyMTDH 适用: 人 IHC, ELISA, IP 宿主: 兔 Polyclonal unconjugated
anti-Metadherin (MTDH) antibodyMTDH 适用: 人 WB, FACS, ICC 宿主: 兔 Monoclonal 24GB455 unconjugated Recombinant Antibody
anti-Metadherin (MTDH) (AA 131-230) antibodyMTDH 适用: 人 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Metadherin (MTDH) antibodyMTDH 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 25GB5810 unconjugated
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应用备注
- Optimal dilution of the AEG-1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the AEG-1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- MTDH (Metadherin (MTDH))
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别名
- AEG-1
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背景
- MTDH (Metadherin), also known as protein LYRIC or astrocyte elevated gene-1 protein (AEG-1) is a protein that in humans is encoded by the MTDH gene. AEG-1 is involved in HIF-1alpha mediated angiogenesis. AEG-1 also interacts with SND1 and involved in RNA-induced silencing complex (RISC) and plays very important role in RISC and miRNA functions. AEG-1 induces an oncogene called Late SV40 factor (LSF/TFCP2) which is involved in thymidylate synthase (TS) induction and DNA biosynthesis synthesis. Late SV40 factor (LSF/TFCP2) enhances angiogenesis by transcriptionally up-regulating matrix metalloproteinase-9 (MMP9). AEG-1 acts as an oncogene in melanoma, malignant glioma, breast cancer and hepatocellular carcinoma. It is highly expressed in these cancers and helps in progression and development of these cancers. It is induced by c-Myc oncogene and plays very important role in anchorage independent growth of cancer cells.
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UniProt
- Q86UE4
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途径
- Cellular Response to Molecule of Bacterial Origin, Cell-Cell Junction Organization
抗原
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