BCOR 抗体 (AA 100-400)
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北京 101111
Quick Overview for BCOR 抗体 (AA 100-400) (ABIN7869872)
抗原
See all BCOR 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 100-400
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原理
- BCOR Antibody / BCL-6 corepressor
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纯化方法
- Protein A/G affinity
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免疫原
- A recombinant partial protein sequence (within amino acids 100-400) from the human protein was used as the immunogen for the BCOR antibody.
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亚型
- IgG2, kappa
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anti-BCL6 Co-Repressor (BCOR) (AA 1107-1137) antibody
BCOR 适用: 人, 小鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB19040 unconjugated
anti-BCL6 Co-Repressor (BCOR) (AA 1361-1460) antibodyBCOR 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-BCL6 Co-Repressor (BCOR) (Internal Region) antibodyBCOR 适用: 人, 小鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-BCL6 Co-Repressor (BCOR) (N-Term) antibodyVerified BCOR 适用: 人 ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-BCL6 Co-Repressor (BCOR) (AA 1-1004) antibodyBCOR 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-BCL6 Co-Repressor (BCOR) (AA 1553-1755) antibodyBCOR 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-BCL6 Co-Repressor (BCOR) (AA 25-75) antibodyBCOR 适用: 人 IHC, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-BCL6 Co-Repressor (BCOR) (Internal Region) antibodyBCOR 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-BCL6 Co-Repressor (BCOR) (Internal Region) antibodyBCOR 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-BCL6 Co-Repressor (BCOR) (AA 1705-1755) antibodyBCOR 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the BCOR antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the BCOR antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- BCOR (BCL6 Co-Repressor (BCOR))
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别名
- BCOR
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背景
- Bcl-6, a transcriptional repressor, can promote or inhibit apoptosis depending on the cell type and also plays an important role in normal immune responses. Bcl-6 negatively regulates NFkB expression, thereby inhibiting NFkB-mediated cellular functions and is frequently found to be deregulated in non-Hodgkin's lymphoma. BCoR (Bcl-6 corepressor) is a 1,755 amino acid protein that associates with histone deacetylases (HDACs) to transcriptionally repress Bcl-6. With ubiquitous expression, BCoR is localized to the nucleus where it interacts with other proteins through its three ANK repeat domains. Mutations in the gene encoding BCoR result in microphthalmia with associated anomalies 2, also known as anophthalmia, which is characterized by variable features, such as renal aplasia, mental retardation, hyospadias, microencephaly and cryptorchidism. There are four isoforms of BCoR which are produced as a result of alternative splicing events.
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UniProt
- Q6W2J9
抗原
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