PRAME 抗体 (AA 100-250)
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北京 101111
Quick Overview for PRAME 抗体 (AA 100-250) (ABIN7869792)
抗原
See all PRAME 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- AA 100-250
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原理
- PRAME Antibody / OIP-4 (azide and preservative free)
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纯化方法
- Protein A/G affinity
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免疫原
- A recombinant fragment (within amino acids 100-250) of human PRAME protein was used as the immunogen for the PRAME antibody.
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亚型
- IgG2b, kappa
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anti-Preferentially Expressed Antigen in Melanoma (PRAME) (AA 416-502) antibody
PRAME 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Preferentially Expressed Antigen in Melanoma (PRAME) (AA 151-250) antibodyPRAME 适用: 人, 小鼠 ELISA, FACS, IHC (p), IF (cc), IF (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Preferentially Expressed Antigen in Melanoma (PRAME) (AA 1-509) antibodyPRAME 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Preferentially Expressed Antigen in Melanoma (PRAME) (AA 1-509) antibodyPRAME 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Preferentially Expressed Antigen in Melanoma (PRAME) (AA 476-502), (C-Term) antibodyPRAME 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB18763 unconjugated
anti-Preferentially Expressed Antigen in Melanoma (PRAME) (AA 1-509) antibodyPRAME 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Preferentially Expressed Antigen in Melanoma (PRAME) antibodyPRAME 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB4420 unconjugated Recombinant Antibody
anti-Preferentially Expressed Antigen in Melanoma (PRAME) (AA 416-502) antibodyPRAME 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Preferentially Expressed Antigen in Melanoma (PRAME) (AA 460-510) antibodyPRAME 适用: 人, Cow, 马, 猴, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-Preferentially Expressed Antigen in Melanoma (PRAME) (N-Term) antibodyPRAME 适用: 人, 大鼠, Cow, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the PRAME antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Aliquot the PRAME antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- PRAME (Preferentially Expressed Antigen in Melanoma (PRAME))
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别名
- PRAME
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背景
- Functions as a transcriptional repressor, inhibiting the signaling of retinoic acid through the retinoic acid receptors RARA, RARB and RARG. Prevents retinoic acid-induced cell proliferation arrest, differentiation and apoptosis. This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants.
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UniProt
- P78395
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途径
- Retinoic Acid Receptor Signaling Pathway, Nuclear Hormone Receptor Binding
抗原
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