MT-ND3 抗体 (AA 10-38)
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北京 101111
Quick Overview for MT-ND3 抗体 (AA 10-38) (ABIN7869699)
抗原
See all MT-ND3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 10-38
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原理
- MT-ND3 Antibody / NADH-ubiquinone oxidoreductase chain 3
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纯化方法
- Antigen affinity
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免疫原
- A portion of amino acids 10-38 from the human protein was used as the immunogen for this MT-ND3 antibody.
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亚型
- Ig Fraction
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应用备注
- The stated application concentrations are suggested starting amounts. Titration of the MT-ND3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4oC for up to one month. For long term, aliquot the MT-ND3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- MT-ND3 (Mitochondrially Encoded NADH Dehydrogenase 3 (MT-ND3))
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别名
- MT-ND3
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背景
- MT-ND3 is a critical subunit of complex I, acting as a catalyst in the transfer of electrons from NADH to ubiquinone. This process is essential for generating the proton gradient necessary for ATP production. Without MT-ND3, the electron transport chain would not be able to function properly, leading to a decrease in ATP production and ultimately, cellular dysfunction. Research has shown that mutations in the gene encoding MT-ND3 can lead to mitochondrial diseases and a range of health problems, including muscle weakness, neurological disorders, and even premature aging.
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UniProt
- P03897
抗原
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