ARHGEF12 抗体 (AA 10-1426)
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Quick Overview for ARHGEF12 抗体 (AA 10-1426) (ABIN7869682)
抗原
See all ARHGEF12 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 10-1426
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原理
- ARHGEF12 Antibody / LARG
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids 10-1426) was used as the immunogen for the ARHGEF12 antibody.
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亚型
- IgG
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anti-rho Guanine Nucleotide Exchange Factor (GEF) 12 (ARHGEF12) (AA 1302-1501) antibody
ARHGEF12 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 12 (ARHGEF12) antibodyARHGEF12 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 12 (ARHGEF12) (AA 817-916) antibodyARHGEF12 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 12 (ARHGEF12) (Internal Region) antibodyARHGEF12 适用: 人, 小鼠, 大鼠 ELISA, WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 12 (ARHGEF12) (Internal Region) antibodyARHGEF12 适用: 人, 小鼠, 大鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 12 (ARHGEF12) (Internal Region) antibodyARHGEF12 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 12 (ARHGEF12) (AA 1350-1400) antibodyARHGEF12 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 12 (ARHGEF12) (AA 4-254) antibodyARHGEF12 适用: 人, 大鼠 ELISA, WB, FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the ARHGEF12 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the ARHGEF12 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- ARHGEF12 (rho Guanine Nucleotide Exchange Factor (GEF) 12 (ARHGEF12))
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别名
- ARHGEF12
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背景
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ARHGEF12, also known as leukemia-associated Rho guanine nucleotide exchange factor or LARG, is a member of the RhoGEF family involved in the regulation of Rho GTPases. These small signaling proteins are crucial for controlling a variety of cellular processes, including cytoskeletal dynamics, cell polarity, migration, and transcriptional activity. ARHGEF12 acts as a guanine nucleotide exchange factor that specifically activates RhoA, linking it to G protein-coupled receptor signaling pathways and other upstream stimuli.
ARHGEF12 is widely expressed in multiple tissue types and has been implicated in various physiological and pathological conditions, such as embryonic development, wound healing, and cancer progression. Alternative splicing of the ARHGEF12 gene gives rise to several isoforms that may vary in function and cellular localization, making precise detection and characterization essential in research.
A high-quality ARHGEF12 antibody is a critical tool for investigating the diverse roles of this protein in cellular signaling and disease. The ARHGEF12 antibody can be used in western blotting to evaluate protein levels, in immunofluorescence to assess subcellular localization, and in immunohistochemistry for tissue-specific expression profiling. NSJ Bioreagents offers an extensively validated ARHGEF12 antibody designed to provide specificity and reproducibility across multiple experimental platforms.
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UniProt
- Q9NZN5
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途径
- Neurotrophin Signaling Pathway, Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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