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Recombinant Parvin, beta 抗体 (N-Term)

This 兔 单克隆 antibody specifically detects Parvin, beta in IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN7869611
发货至: 中国
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Quick Overview for Recombinant Parvin, beta 抗体 (N-Term) (ABIN7869611)

抗原

See all Parvin, beta (PARVB) 抗体
Parvin, beta (PARVB)

抗体类型

Recombinant Antibody

适用

  • 22
  • 9
  • 9
  • 4
  • 4
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  • 1
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宿主

  • 16
  • 6

克隆类型

  • 13
  • 9
单克隆

标记

  • 22
This Parvin, beta antibody is un-conjugated

应用范围

  • 18
  • 7
  • 5
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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

PARVB-8214R
  • 抗原表位

    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-91, N-Term

    原理

    Beta-Parvin Antibody / PARVB (azide and preservative free)

    纯化方法

    Protein A/G affinity

    免疫原

    The N-terminal region (residues 1-91) of the human protein was used as the immunogen for the Beta-Parvin antibody.

    亚型

    IgG, kappa
  • 应用备注

    Optimal dilution of the Beta-Parvin antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    -20 °C

    储存方法

    Aliquot the Beta-Parvin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    Parvin, beta (PARVB)

    别名

    Beta-Parvin

    背景

    Beta-parvin, also known as affixin, is a focal adhesion protein belonging to a family of ILKbinding proteins that contain tandem calponin homolog domains. Along with Alpha-parvin, Beta-parvin is one of the most widely researched and characterized members of this family. These two proteins interact with the ILK kinase domain in a way that is mutually exclusive and regulates both the activity of the kinase and actin cytoskeleton adhesion. Studies have shown Beta-parvin to be downregulated within human breast cancer cells, and that its expression may influence the progression of breast cancer (Johnstone, 2008). Additional research indicates a critical role for Beta-parvin in the regulation of cardiac contractility when it is in complex with ILK (Hannigan, 2007).

    UniProt

    Q9HBI1
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