Recombinant Parvin, beta 抗体 (N-Term)
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Quick Overview for Recombinant Parvin, beta 抗体 (N-Term) (ABIN7869611)
抗原
See all Parvin, beta (PARVB) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- AA 1-91, N-Term
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原理
- Beta-Parvin Antibody / PARVB (azide and preservative free)
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纯化方法
- Protein A/G affinity
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免疫原
- The N-terminal region (residues 1-91) of the human protein was used as the immunogen for the Beta-Parvin antibody.
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亚型
- IgG, kappa
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应用备注
- Optimal dilution of the Beta-Parvin antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Aliquot the Beta-Parvin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Parvin, beta (PARVB)
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别名
- Beta-Parvin
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背景
- Beta-parvin, also known as affixin, is a focal adhesion protein belonging to a family of ILKbinding proteins that contain tandem calponin homolog domains. Along with Alpha-parvin, Beta-parvin is one of the most widely researched and characterized members of this family. These two proteins interact with the ILK kinase domain in a way that is mutually exclusive and regulates both the activity of the kinase and actin cytoskeleton adhesion. Studies have shown Beta-parvin to be downregulated within human breast cancer cells, and that its expression may influence the progression of breast cancer (Johnstone, 2008). Additional research indicates a critical role for Beta-parvin in the regulation of cardiac contractility when it is in complex with ILK (Hannigan, 2007).
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UniProt
- Q9HBI1
抗原
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