OCRL 抗体 (AA 1-901)
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北京 101111
Quick Overview for OCRL 抗体 (AA 1-901) (ABIN7869609)
抗原
See all OCRL 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-901
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原理
- OCRL-1 Antibody
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纯化方法
- Antigen affinity purified
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免疫原
- E. coli-derived recombinant human protein (amino acids M1-D901) was used as the immunogen for the OCRL-1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the OCRL-1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the OCRL-1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- OCRL (Oculocerebrorenal Syndrome of Lowe (OCRL))
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别名
- OCRL-1
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背景
- Inositol polyphosphate 5-phosphatase OCRL-1, also known as Lowe oculocerebrorenal syndrome protein, is an enzyme encoded by the OCRL gene located on the X chromosome in humans. This gene encodes an inositol polyphosphate 5-phosphatase. This protein is involved in regulating membrane trafficking and is located in numerous subcellular locations including the trans-Golgi network, clathrin-coated vesicles and endosomes and the plasma membrane. This protein may also play a role in primary cilium formation. Mutations in this gene cause oculocerebrorenal syndrome of Lowe and also Dent disease. Alternate splicing results in multiple transcript variants.
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UniProt
- Q01968
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途径
- Inositol Metabolic Process
抗原
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