Dynein Light Chain 1 (AA 1-89), (Light Chain) 抗体
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Quick Overview for Dynein Light Chain 1 (AA 1-89), (Light Chain) 抗体 (ABIN7869607)
抗原
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-89, Light Chain
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原理
- Dynein light chain 1 Antibody / DYNLL1
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纯化方法
- Affinity purified
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免疫原
- Recombinant human protein (amino acids M1-G89) was used as the immunogen for the Dynein light chain 1 antibody.
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亚型
- IgG2b
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应用备注
- Optimal dilution of the Dynein light chain 1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Dynein light chain 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- Dynein Light Chain 1
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背景
- Dynein light chain 1, cytoplasmic is a protein that in humans is encoded by the DYNLL1 gene. Cytoplasmic dyneins are large enzyme complexes with a molecular mass of about 1,200 kD. They contain two force-producing heads formed primarily from dynein heavy chains, and stalks linking the heads to a basal domain, which contains a varying number of accessory intermediate chains. The complex is involved in intracellular transport and motility. The protein described in this record is a light chain and exists as part of this complex but also physically interacts with and inhibits the activity of neuronal nitric oxide synthase. Binding of this protein destabilizes the neuronal nitric oxide synthase dimer, a conformation necessary for activity, and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity. Alternate transcriptional splice variants have been characterized.
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UniProt
- P63167
抗原
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